Look people, “Atg” is an abbreviation for “autophagy-related.” That’s it.
نویسندگان
چکیده
منابع مشابه
Upregulation of Autophagy-Related Gene-5 (ATG-5) Is Associated with Chemoresistance in Human Gastric Cancer
Autophagy-related gene-5 (ATG-5) is one of the key regulators of autophagic cell death. It has been widely regarded as a protective molecular mechanism for tumor cells during the course of chemotherapy. In the present study, we investigated the expression pattern of ATG-5 and multidrug resistance-associated protein-1 (MRP-1) in 135 gastric cancers (GC) patients who were treated with epirubicin,...
متن کاملNo ATG is an island--the connection of autophagy with diverse pathways and functions.
The International Symposium on Auto phagy (ISA) is an important meeting with a long history devoted solely to the topic of autophagy. Yoshimori Ohsumi (Tokyo Institute of Technology, Japan), who identified a series of autophagyrelated genes (ATG genes) in yeast [1], proposed and organized the first ISA in Okazaki, Japan, in 1997. Over the years, the ISA sym posia have witnessed the explosive...
متن کاملThree-Axis Model for Atg Recruitment in Autophagy against Salmonella
Salmonella enterica serovar Typhimurium enter epithelial cells and take up residence there. Within epithelial cells, a portion of the bacteria are surrounded by an autophagosome-like double-membrane structure, and they are still residing within the Salmonella-containing vacuole (SCV). In this paper, we will discuss how the autophagy machinery is recruited in proximity to Salmonella. The formati...
متن کاملAutophagy: Starvation Relieves Transcriptional Repression of ATG Genes
Autophagy is a highly regulated process about which relatively little is known, particularly concerning the transcriptional control of autophagy regulation. A new study identifies a key regulator of the expression of autophagy-related genes, thereby providing insights into the signalling pathways modulating autophagy.
متن کاملComparing Serum Levels of Autophagy-Related Gene 5 in People With and Without Helicobacter Pylori Infection
Background: Laboratory studies have shown that gastric epithelial infection cells with Helicobacter pylori (H. pylori) can increase autophagy. Disruption in this process can cause various diseases, including cancer. Objective: This study aims to compare the serum level of Autophag -Related Gene 5 (ATG5) in individuals with and without H. pylori infection. Methods: This case-control pilot stud...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2012
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.21812